Convalescent Plasma Donation Implication

Interesting information from the American Red Cross society:

Convalescent plasma treatments allow doctors to take plasma from someone who already had COVID-19 and transfer their antibodies to a patient who recently contracted the virus.

Can I donate COVID-19 convalescent plasma if I have received the vaccination?

At this time individuals who have received a COVID-19 vaccine are not able to donate convalescent plasma with the Red Cross.

This is to ensure that antibodies collected from donors have sufficient antibodies directly related to their immune response to a COVID-19 infection and not just the vaccine, as antibodies from an infection and antibodies from a vaccine are not the same.

Antibodies that an individual produces when they've been exposed to the virus are slightly different from the antibodies that an individual produces when they've been vaccinated.

When an individual has been infected with a virus, they produce antibodies to multiple regions of a virus.

At the Red Cross, we use two antibody tests to generate our results on blood, platelet and plasma donations.

One test - Ortho's total test - detects antibodies to the spike protein of the virus.

The other detects antibodies to a different protein of the virus called the nucleocapsid protein.

If a donor has had the COVID-19 vaccine, they will generate an antibody against the spike protein but not the nucleocapsid protein, which will only occur in the event of a COVID-19 infection.

Read : You can donate blood, but not convalescent plasma, after getting COVID-19 vaccine

American Red Cross : Can I donate after receiving a COVID-19 vaccine? 

https://www.redcrossblood.org/local-homepage/news/article/covid-19-vaccination-guide-blood-donation.html<br>

https://www.redcrossblood.org/local-homepage/news/article/covid-19-vaccination-guide-blood-donation.html